Caries vaccine the strategic prevention of dental caries and development of dental caries vaccine from evolution to culmination garewal ripin garewal jessica somani rani isbn 9783844388961 kostenloser versand fur alle bucher mit versand und verkauf duch amazon. Huge amounts of money and time are spent in treating dental caries hence the prevention and control of dental caries is the main aim of public health eventually the ultimate objective of public health is the elimination of the disease itself recently dental caries vaccines have been developed for the prevention of dental caries these dental caries vaccines are still in the early stages. Current strategies for immunisation against dental caries are using these virulence factors as key antigens and incorporating them into novel mucosal vaccine systems and delivering them with or without adjuvants to mucosal iga inductive sites the most popular routes of mucosal immunisation are via the oral or nasal route the mucosal immune system is functional in newborn infants who develop salivary iga antibodies as they become colonised by oral micro organisms mucosal immunisation . Streptococcus mutans play a key role for the development of dental caries and that a vaccine directed against this microorganism could be a valuable adjunct to existing preventive measures in some. The evidence of a specific bacterial cause of dental caries and of the function of the salivary glands as an effector site of the mucosal immune system has provided a scientific basis for the development of a vaccine against this highly prevalent and costly oral disease research efforts towards developing an effective and safe caries vaccine have been facilitated by progress in molecular biology with the cloning and functional characterization of virulence factors from mutans streptococci
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